Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29702411 | 0.82 | MME (0.36) | NAMPTTRPM8MMEALDH1A1KDM4E | |
| SCHEMBL5431495 | 0.74 | CA12 (0.50) | NAMPTTRPM8ALDH1A1KDM4ETDP1 | |
| SCHEMBL19699077 | 0.73 | NLRP3 (0.47) | ALDH1A1KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL93942 | 0.73 | SCN9A (0.39) | ALDH1A1KDM4EMEN1KMT2ASCN9A | |
| SCHEMBL93941 | 0.73 | SCN9A (0.39) | ALDH1A1KDM4EMEN1KMT2ASCN9A | |
| Hydrochloric Acid SCHEMBL28535122 | 0.72 | SCN9A (0.38) | ALDH1A1KDM4EMEN1KMT2ASCN9A | |
| Hydrochloric Acid SCHEMBL3069711 | 0.72 | SCN9A (0.38) | ALDH1A1KDM4EMEN1KMT2ASCN9A | |
| Hydrochloric Acid SCHEMBL3069712 | 0.72 | SCN9A (0.38) | ALDH1A1KDM4EMEN1KMT2ASCN9A | |
| SCHEMBL13083202 | 0.71 | SCN9A (0.40) | ALDH1A1KDM4EMEN1KMT2ASCN9A | |
| SCHEMBL93943 | 0.70 | CYP3A4 (0.65) | ALDH1A1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384028-B1 | TREATMENT OF CARDIOVASCULAR DISORDERS, ANTICOAGULANTS AND VALVE REPLACEMENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| WO-1996029309-A1 | N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-26 | — | — | WO | disclosed |