Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 3/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7428333 | 0.99 | CSNK1E (0.43) | CSNK1ERENEPHX1SLC15A1KMT2A | |
| SCHEMBL7387419 | 0.75 | CYP1A2 (0.54) | RENKMT2AALDH1A1GAARAB9A | |
| SCHEMBL4695118 | 0.74 | ANPEP (0.54) | CSNK1EKMT2AANPEPERAP2F2 | |
| SCHEMBL4693744 | 0.74 | ANPEP (0.54) | CSNK1EKMT2AANPEPERAP2F2 | |
| SCHEMBL4047072 | 0.74 | ANPEP (0.54) | CSNK1EKMT2AANPEPERAP2F2 | |
| SCHEMBL5720870 | 0.74 | ANPEP (0.54) | CSNK1EKMT2AANPEPERAP2F2 | |
| SCHEMBL10871667 | 0.74 | EPHX2 (0.45) | CSNK1EEPHX1SLC15A1SMN1; SMN2ANPEP | |
| SCHEMBL27421495 | 0.74 | CSNK1E (0.49) | CSNK1EEPHX1SLC15A1ANPEPALPI | |
| Hydrochloric Acid SCHEMBL5930110 | 0.73 | ANPEP (0.53) | CSNK1EKMT2AANPEPERAP2F2 | |
| SCHEMBL5217605 | 0.73 | SLC6A4 (0.48) | CSNK1ERAB9AMETAP2F2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826815-A | HYPOTENSIVE | ABBOTT LABORATORIES (US) | 1989-05-02 | — | — | US | disclosed |
| US-4645759-A | HYPOTENSIVE AGENTS | ABBOTT LABORATORIES (US) | 1987-02-24 | — | — | US | disclosed |
| EP-0172347-A2 | Renin inhibiting compounds | ABBOTT LABORATORIES (US) | 1986-02-26 | — | — | EP | disclosed |