Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.36 |
| ▸ | TUBB | P07437 | 3/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10380146 | 1.00 | KDM1A (0.40) | KDM1AMAOBMAOAALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7444790 | 0.99 | HTR2C (0.39) | KDM1AMAOBMAOAALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7311498 | 0.99 | HTR2C (0.39) | KDM1AMAOBMAOAALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9802220 | 0.86 | HTR2A (0.47) | HTR2AHTR2CHTR2B | |
| SCHEMBL7313122 | 0.78 | ALDH1A1 (0.38) | KDM1AMAOBMAOAALDH1A1L3MBTL1 | |
| SCHEMBL7321018 | 0.78 | ALDH1A1 (0.46) | KDM1AMAOBMAOAALDH1A1L3MBTL1 | |
| SCHEMBL7321028 | 0.76 | ALDH1A1 (0.39) | KDM1AMAOBMAOAALDH1A1L3MBTL1 | |
| SCHEMBL9802420 | 0.75 | DRD1 (0.41) | MAOBHTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL7320424 | 0.75 | CHRNA7 (0.47) | MAOBALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7451338 | 0.74 | HTR2A (0.40) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996038435-A1 | DOPAMINE AGONISTS | ABBOTT LABORATORIES (US) | 1996-12-05 | — | — | WO | disclosed |
| EP-0474767-B1 | DOPAMINE AGONISTS | ABBOTT LAB (US) | 1996-02-21 | — | — | EP | disclosed |