Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31419879 | 0.87 | LMNA (0.53) | NOS1LMNATSHRMAPTNPSR1 | |
| SCHEMBL11471053 | 0.83 | HTT (0.58) | LMNATSHRMAPTHTTNPSR1 | |
| SCHEMBL7942147 | 0.79 | HTT (0.45) | LMNATSHRMAPTHTTNPSR1 | |
| SCHEMBL9351961 | 0.79 | HTT (0.44) | LMNATSHRMAPTHTTNPSR1 | |
| SCHEMBL9565592 | 0.73 | SLC29A1 (0.49) | LMNATSHRMAPTHTTNPSR1 | |
| SCHEMBL17822445 | 0.73 | LMNA (0.55) | NOS1LMNATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL17822430 | 0.73 | LMNA (0.55) | NOS1LMNATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL9159049 | 0.73 | HTT (0.61) | LMNATSHRMAPTHTTNPSR1 | |
| SCHEMBL8830437 | 0.72 | CHUK (0.50) | NOS1LMNAHTTALOX15JAK3 | |
| SCHEMBL8826309 | 0.72 | CHUK (0.50) | NOS1LMNAHTTALOX15JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998019672-A9 | NITROSATED AND NITROSYLATED PHOSPHODIESTERASE INHIBITOR COMPOUNDS, COMPOSITIONS AND THEIR USES | — | 1998-09-11 | — | — | WO | disclosed |