Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | TRHR | P34981 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443716 | 1.00 | CAPN1 (0.40) | CAPN1CTSBTRHRSLC6A2ELANE | |
| SCHEMBL7281202 | 0.92 | CAPN1 (0.41) | CAPN1CTSBTRHRSLC6A2ELANE | |
| SCHEMBL7281210 | 0.92 | CAPN1 (0.41) | CAPN1CTSBTRHRSLC6A2ELANE | |
| SCHEMBL7282406 | 0.86 | CAPN1 (0.41) | CAPN1CTSBTRHRSLC6A2ELANE | |
| SCHEMBL7282397 | 0.86 | CAPN1 (0.41) | CAPN1CTSBTRHRSLC6A2ELANE | |
| SCHEMBL7274041 | 0.84 | ELANE (0.44) | ELANE | |
| SCHEMBL7274032 | 0.84 | ELANE (0.44) | ELANE | |
| SCHEMBL7276794 | 0.81 | XIAP (0.46) | TRHRELANE | |
| SCHEMBL7276782 | 0.81 | XIAP (0.46) | TRHRELANE | |
| SCHEMBL7435810 | 0.80 | TRHR (0.43) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151497-A | Central nervous system disorders, antidepressants, epilepsy and cognition activators | JAPAN TOBACCO INC. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0473993-A2 | Novel peptide derivatives and their pharmaceutical use | Japan Tobacco Inc. (JP) | 1992-03-11 | — | — | EP | disclosed |