Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432625 | 0.87 | KMT2A (0.56) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL6847731 | 0.82 | KMT2A (0.60) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL9036006 | 0.81 | MAPT (0.51) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL5358583 | 0.81 | KMT2A (0.53) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL15988636 | 0.78 | GSK3B (0.73) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL982447 | 0.73 | GSK3B (0.71) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL17033397 | 0.73 | ALDH1A1 (0.72) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL20460413 | 0.72 | HPGD (0.96) | ALDH1A1MAPTHPGDLMNAPOLB | |
| SCHEMBL12123615 | 0.72 | ALDH1A1 (0.59) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL5954595 | 0.72 | ALDH1A1 (0.71) | KMT2AMEN1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571685-A1 | Aryloxyheteroarylpropylamines, their preparation and use | NOVO NORDISK A/S (DK) | 1993-12-01 | — | — | EP | disclosed |