Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL9325931 | 0.93 | REN (0.82) | REN | |
| Acetic Acid SCHEMBL9326366 | 0.89 | REN (0.71) | REN | |
| Acetic Acid SCHEMBL9326712 | 0.88 | REN (0.73) | REN | |
| Acetic Acid SCHEMBL9325957 | 0.84 | REN (0.97) | REN | |
| Acetic Acid SCHEMBL9326323 | 0.84 | REN (0.80) | REN | |
| Acetic Acid SCHEMBL9325901 | 0.84 | REN (0.67) | REN | |
| SCHEMBL9327709 | 0.83 | REN (0.83) | REN | |
| Acetic Acid SCHEMBL9326611 | 0.83 | REN (0.80) | REN | |
| Acetic Acid SCHEMBL9326716 | 0.81 | REN (0.71) | REN | |
| SCHEMBL7267778 | 0.81 | REN (0.66) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634175-B1 | Pharmaceutical combination, containing a renin-angiotensin-system inhibitor and an endothelin antagonist | HOFFMANN LA ROCHE (CH) | 2001-01-10 | — | — | EP | disclosed |
| US-5696116-A | TREATING DISORDERS ASSOCIATED WITH VASOCONSTRICTION | HOFFMANN-LA ROCHE INC. (US) | 1997-12-09 | — | — | US | disclosed |