Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31369696 | 1.00 | EGLN1 (0.44) | EGLN1GAAMAPTOPRM1OPRD1 | |
| SCHEMBL31370222 | 1.00 | EGLN1 (0.44) | EGLN1GAAMAPTOPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL8488033 | 0.98 | EGLN1 (0.43) | EGLN1GAAMAPTOPRM1OPRD1 | |
| SCHEMBL31370224 | 0.94 | EGLN1 (0.44) | EGLN1GAAMAPTOPRM1OPRD1 | |
| SCHEMBL539874 | 0.82 | KCNH2 (0.46) | EGLN1GAAMAPTOPRM1OPRD1 | |
| SCHEMBL29589035 | 0.82 | KCNH2 (0.46) | EGLN1GAAMAPTOPRM1OPRD1 | |
| SCHEMBL539875 | 0.82 | KCNH2 (0.46) | EGLN1GAAMAPTOPRM1OPRD1 | |
| SCHEMBL29588998 | 0.82 | KCNH2 (0.46) | EGLN1GAAMAPTOPRM1OPRD1 | |
| SCHEMBL1280052 | 0.82 | KCNH2 (0.46) | EGLN1GAAMAPTOPRM1OPRD1 | |
| SCHEMBL29584516 | 0.82 | KCNH2 (0.46) | EGLN1GAAMAPTOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401676-B1 | Enzyme inhibitors | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1995-01-11 | — | — | EP | disclosed |
| US-5212157-A | Tetrapeptides as inhibitors of HIV | BIO-MEGA, INC. (CA) | 1993-05-18 | — | — | US | disclosed |
| EP-0401676-A1 | Enzyme inhibitors | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1990-12-12 | — | — | EP | disclosed |