Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1581790 | 0.83 | ALDH1A1 (0.47) | ALDH1A1HTTL3MBTL1KMT2ALMNA | |
| SCHEMBL14143389 | 0.76 | ALDH1A1 (0.42) | ALDH1A1HTTL3MBTL1KMT2ALMNA | |
| SCHEMBL4059035 | 0.75 | ALDH1A1 (0.45) | ALDH1A1HTTL3MBTL1KMT2ALMNA | |
| SCHEMBL17141421 | 0.70 | ALDH1A1 (0.40) | ALDH1A1HTTL3MBTL1KMT2ALMNA | |
| SCHEMBL25078495 | 0.67 | — | — | |
| SCHEMBL542127 | 0.67 | — | — | |
| SCHEMBL1369329 | 0.67 | — | — | |
| SCHEMBL27436012 | 0.66 | BTK (0.48) | ALDH1A1KMT2ALMNAMEN1NPC1 | |
| SCHEMBL3169587 | 0.66 | AKR1B1 (0.46) | ALDH1A1HTTL3MBTL1KMT2ALMNA | |
| SCHEMBL25668259 | 0.66 | OGA (0.36) | KMT2ALMNAMEN1PDE3APDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326760-A | Aminobutanoic acid compounds having metalloprotease inhibiting properties | GLAXO, INC. (US) | 1994-07-05 | — | — | US | disclosed |
| WO-1994000119-A1 | AMINOBUTANOIC ACID COMPOUNDS HAVING METALLOPROTEASE INHIBITING PROPERTIES | GLAXO INC. (US) | 1994-01-06 | — | — | WO | disclosed |
| US-4690917-A | Imidazopyridayine derivatives having antiviral activity | GLAXO GROUP LIMITED (GB) | 1987-09-01 | — | — | US | disclosed |