Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449965 | 0.91 | ITGB3 (0.58) | ITGB3ITGA2BMEN1KMT2AFPR2 | |
| SCHEMBL7447038 | 0.90 | ITGB3 (0.72) | ITGB3ITGA2BMEN1KMT2AFPR2 | |
| Acetic Acid SCHEMBL7445840 | 0.90 | ITGB3 (0.69) | ITGB3ITGA2BFPR2FPR1HDAC6 | |
| SCHEMBL7449970 | 0.90 | ITGB3 (0.62) | ITGB3ITGA2BMEN1KMT2AFPR2 | |
| SCHEMBL7447482 | 0.89 | ITGB3 (0.61) | ITGB3ITGA2BFPR2FPR1HDAC6 | |
| SCHEMBL7450950 | 0.89 | ITGB3 (0.63) | ITGB3ITGA2BFPR2FPR1HDAC6 | |
| SCHEMBL7446910 | 0.89 | ITGB3 (0.57) | ITGB3ITGA2BFPR2FPR1HDAC6 | |
| SCHEMBL8101804 | 0.88 | ITGB3 (0.60) | ITGB3ITGA2BFPR2FPR1HDAC6 | |
| SCHEMBL8093830 | 0.88 | ITGB3 (0.60) | ITGB3ITGA2BFPR2FPR1HDAC6 | |
| SCHEMBL7455082 | 0.88 | ITGB3 (0.65) | ITGB3ITGA2BMEN1KMT2AFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025358-A | Double prodrugs of potent GP IIb/IIIa antagonists | G. D. SEARLE & CO. (US) | 2000-02-15 | — | — | US | claimed |
| WO-1999064397-A1 | DOUBLE PRODRUGS OF POTENT GPIIb/IIIa ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-12-16 | — | — | WO | claimed |
| US-6025358-A | Double prodrugs of potent GP IIb/IIIa antagonists | G. D. SEARLE & CO. (US) | 2000-02-15 | — | — | US | disclosed |
| WO-1999064397-A1 | DOUBLE PRODRUGS OF POTENT GPIIb/IIIa ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-12-16 | — | — | WO | disclosed |