Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | ADA | P00813 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7457097 | 0.92 | KMT2A (0.41) | KMT2APSMB5ADAKDM4EALDH1A1 | |
| SCHEMBL7449547 | 0.91 | ADA (0.45) | KMT2APSMB5ADAKDM4EALDH1A1 | |
| SCHEMBL7457345 | 0.91 | ADA (0.45) | KMT2APSMB5ADAKDM4EALDH1A1 | |
| SCHEMBL7448911 | 0.86 | ADA (0.46) | KMT2AADAKDM4EALDH1A1MAPK8 | |
| SCHEMBL7448692 | 0.80 | ADA (0.38) | KMT2AADAKDM4EALDH1A1HPGD | |
| SCHEMBL7827666 | 0.80 | NR3C2 (0.39) | HPGD | |
| SCHEMBL7452297 | 0.79 | DAO (0.35) | KMT2AADAALDH1A1MEN1SLC1A3 | |
| SCHEMBL7448884 | 0.79 | SLC6A2 (0.38) | ADA | |
| SCHEMBL7450783 | 0.78 | ADA (0.44) | KMT2AADA | |
| SCHEMBL7449954 | 0.76 | KMT2A (0.39) | KMT2AKDM4EALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098885-A1 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-16 | — | — | EP | disclosed |
| WO-2001026605-A2 | IMMUNOSUPPRESSIVE COMPOSITION CONTAINING IL-2 INHIBITOR AND AN ADENOSINE DEAMINASE INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-19 | — | — | WO | disclosed |
| WO-2000005217-A1 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-02-03 | — | — | WO | disclosed |