Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449547 | 1.00 | ADA (0.45) | ADAKMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7457097 | 0.93 | KMT2A (0.41) | ADAKMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7444334 | 0.91 | KMT2A (0.41) | ADAKMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7448692 | 0.90 | ADA (0.38) | ADAKMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7452297 | 0.89 | DAO (0.35) | ADAKMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7448884 | 0.88 | SLC6A2 (0.38) | ADA | |
| SCHEMBL7450783 | 0.87 | ADA (0.44) | ADAKMT2A | |
| SCHEMBL7827666 | 0.87 | NR3C2 (0.39) | HPGDL3MBTL1 | |
| SCHEMBL7449954 | 0.85 | KMT2A (0.39) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL7453359 | 0.85 | PDE4A (0.37) | ADAKMT2ASLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001026605-A2 | IMMUNOSUPPRESSIVE COMPOSITION CONTAINING IL-2 INHIBITOR AND AN ADENOSINE DEAMINASE INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-19 | — | — | WO | disclosed |