Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | IL1RN | P18510 | 1/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27476684 | 0.91 | ELANE (0.62) | ELANENPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL2801105 | 0.87 | ELANE (0.62) | ELANENPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL24740161 | 0.87 | ELANE (0.62) | ELANENPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7229401 | 0.87 | ELANE (0.60) | ELANENPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL6556136 | 0.83 | ELANE (0.62) | ELANENPC1RAB9ACYP2C9CYP2C19 | |
| SCHEMBL7276615 | 0.83 | NPC1 (0.49) | ELANENPC1RAB9AF2PRSS1 | |
| SCHEMBL7230385 | 0.82 | ELANE (0.47) | ELANENPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL16751092 | 0.81 | ELANE (0.61) | ELANENPC1RAB9AIL1RNERAP2 | |
| SCHEMBL15418794 | 0.80 | ELANE (0.65) | ELANENPC1RAB9AIL1RNERAP2 | |
| SCHEMBL8646687 | 0.79 | NPC1 (0.62) | ELANENPC1RAB9AALDH1A1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993021213-A1 | ALPHA-AMINOBORONIC ACID PEPTIDES AND THEIR USE AS ELASTASE INHIBITORS | ZENECA LIMITED (GB) | 1993-10-28 | — | — | WO | disclosed |