Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 4/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 3/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506254 | 0.91 | ELANE (0.41) | ELANECTRB1TACR1 | |
| SCHEMBL7444283 | 0.87 | ELANE (0.51) | ELANECTRB1TACR1HCRTR1CTSS | |
| SCHEMBL6505024 | 0.86 | ELANE (0.40) | ELANECTRB1TACR1KMT2AMEN1 | |
| SCHEMBL6800996 | 0.85 | ELANE (0.41) | ELANECTRB1TACR1HCRTR1 | |
| SCHEMBL6507241 | 0.83 | ELANE (0.40) | ELANECTRB1TACR1 | |
| SCHEMBL6801500 | 0.83 | ELANE (0.42) | ELANECTRB1TACR1HCRTR1KMT2A | |
| SCHEMBL6497427 | 0.83 | ELANE (0.47) | ELANECTRB1TACR1KMT2AMEN1 | |
| SCHEMBL7447429 | 0.83 | ELANE (0.47) | ELANECTRB1TACR1KMT2AMEN1 | |
| SCHEMBL6806041 | 0.83 | ELANE (0.40) | ELANECTRB1TACR1HCRTR1KMT2A | |
| SCHEMBL6503633 | 0.83 | USP2 (0.41) | ELANETACR1CTSBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996037485-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1996-11-28 | — | — | WO | claimed |
| WO-1996037485-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1996-11-28 | — | — | WO | disclosed |