Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497427 | 1.00 | ELANE (0.47) | ELANECTRB1CACNA1BNPC1PTPN1 | |
| SCHEMBL7444283 | 0.95 | ELANE (0.51) | ELANECTRB1MEN1KMT2ATACR1 | |
| SCHEMBL6498129 | 0.92 | ELANE (0.44) | ELANECTRB1NPC1TACR1 | |
| SCHEMBL7449581 | 0.92 | ELANE (0.46) | ELANECTRB1PTPN1PTPN2ALDH1A1 | |
| SCHEMBL6498606 | 0.90 | ELANE (0.59) | ELANECTRB1CACNA1BNPC1PTPN1 | |
| SCHEMBL7548057 | 0.90 | ELANE (0.42) | ELANECTRB1NPC1MEN1KMT2A | |
| SCHEMBL6505687 | 0.89 | ELANE (0.49) | ELANECTRB1PTPN1KMT2AITGA4 | |
| SCHEMBL7451067 | 0.88 | ELANE (0.41) | ELANECTRB1NPC1LMNAMEN1 | |
| SCHEMBL7829601 | 0.88 | ELANE (0.49) | ELANECTRB1MEN1KMT2ATACR1 | |
| SCHEMBL6807471 | 0.87 | ELANE (0.42) | ELANECTRB1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996037485-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1996-11-28 | — | — | WO | claimed |