Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.52 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.52 |
| ▸ | FAP | Q12884 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7499435 | 0.90 | ACE (0.49) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL7437025 | 0.87 | DPP4 (0.52) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9450506 | 0.85 | DPP4 (0.50) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL7448400 | 0.83 | PREP (0.54) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL7445441 | 0.81 | DPP4 (0.51) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL7502395 | 0.81 | ACE (0.56) | FAPACE2ACE | |
| SCHEMBL7500726 | 0.81 | DPP4 (0.50) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL7506781 | 0.81 | DPP4 (0.50) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9450539 | 0.80 | DPP4 (0.47) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9407289 | 0.80 | DPP4 (0.59) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748333-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2000-05-10 | — | — | EP | disclosed |
| EP-0748333-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995023809-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1995-09-08 | — | — | WO | disclosed |