Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 5/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | GPR132 | Q9UNW8 | 4/20 | 0.42 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.42 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444796 | 0.90 | DPP4 (0.52) | ACEDPP4DPP8DPP9DPP7 | |
| SCHEMBL7502395 | 0.88 | ACE (0.56) | ACEACE2ECE1FAP | |
| SCHEMBL7442239 | 0.87 | ACE (0.62) | ACETAAR1ACE2 | |
| SCHEMBL7437025 | 0.81 | DPP4 (0.52) | ACEDPP4DPP8DPP9DPP7 | |
| SCHEMBL9450506 | 0.78 | DPP4 (0.50) | ACEDPP4DPP8DPP9DPP7 | |
| SCHEMBL7448400 | 0.77 | PREP (0.54) | ACEDPP4DPP8DPP9DPP7 | |
| SCHEMBL23973837 | 0.76 | ALDH1A1 (0.53) | SIGMAR1ECE1GPR132CMKLR2CMKLR1 | |
| SCHEMBL7445441 | 0.75 | DPP4 (0.51) | ACEDPP4DPP8DPP9DPP7 | |
| SCHEMBL7500726 | 0.74 | DPP4 (0.50) | ACEDPP4DPP8DPP9DPP7 | |
| SCHEMBL7506781 | 0.74 | DPP4 (0.50) | ACEDPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748333-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2000-05-10 | — | — | EP | disclosed |
| EP-0748333-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995023809-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1995-09-08 | — | — | WO | disclosed |