Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449789 | 0.75 | PRNP (0.57) | PRNPKMT2AMEN1RXFP1NPSR1 | |
| SCHEMBL8764852 | 0.69 | PRNP (0.57) | PRNPKMT2AMEN1RXFP1NPSR1 | |
| SCHEMBL7445079 | 0.67 | PRNP (0.47) | PRNPKMT2AMEN1RXFP1NPSR1 | |
| SCHEMBL19810775 | 0.67 | PRNP (0.57) | PRNPKMT2AMEN1RXFP1NPSR1 | |
| SCHEMBL29981129 | 0.67 | PRNP (0.57) | PRNPKMT2AMEN1RXFP1NPSR1 | |
| SCHEMBL7052149 | 0.66 | PRNP (0.46) | PRNPKMT2AMEN1RXFP1NPSR1 | |
| SCHEMBL14925239 | 0.64 | CYSLTR2 (0.55) | CYP1A2CYSLTR2CYSLTR1 | |
| SCHEMBL9286381 | 0.64 | PRNP (1.00) | PRNPKMT2AMEN1RXFP1NPSR1 | |
| SCHEMBL1613311 | 0.63 | PRNP (1.00) | PRNPKMT2AMEN1RXFP1NPSR1 | |
| SCHEMBL7052147 | 0.62 | PRNP (0.47) | PRNPKMT2AMEN1RXFP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712403-A1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX INC (US) | 1996-05-22 | — | — | EP | disclosed |
| WO-1995004735-A1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1995-02-16 | — | — | WO | disclosed |