Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 9/20 | 0.55 |
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14925238 | 0.86 | CYSLTR1 (0.48) | CYSLTR2CYSLTR1GPBAR1FFAR1AKR1B1 | |
| SCHEMBL28169944 | 0.76 | CYSLTR1 (0.55) | CYSLTR2CYSLTR1CYP1A2ALOX5GPBAR1 | |
| SCHEMBL3951227 | 0.76 | GPBAR1 (0.52) | CYSLTR2CYSLTR1CYP1A2ALOX5GPBAR1 | |
| SCHEMBL28015630 | 0.76 | GPBAR1 (0.55) | CYSLTR2CYSLTR1CYP1A2ALOX5GPBAR1 | |
| SCHEMBL3951224 | 0.76 | GPBAR1 (0.55) | CYSLTR2CYSLTR1CYP1A2ALOX5GPBAR1 | |
| SCHEMBL24235719 | 0.75 | ALDH1A1 (0.54) | CYP1A2 | |
| SCHEMBL22607077 | 0.75 | ALDH1A1 (0.54) | CYP1A2 | |
| SCHEMBL9286000 | 0.74 | ALDH1A1 (0.58) | CYSLTR2CYSLTR1CYP1A2ALOX5GPBAR1 | |
| SCHEMBL30484922 | 0.72 | KMT2A (0.49) | CYSLTR2CYSLTR1 | |
| SCHEMBL28728446 | 0.72 | CYP1A2 (0.49) | CYSLTR2CYSLTR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993767-B2 | Multiphoton activable quinoline derivatives, their preparation and their uses | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-03-31 | — | — | US | disclosed |
| US-20130116281-A1 | Multiphoton Activable Quinoline Derivatives, Their Preparation and Their Uses | UNIVERSITÉ PARIS CITÉ (FR) | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116281-A1 | Multiphoton Activable Quinoline Derivatives, Their Preparation and Their Uses | NQO2, ACHE, NQO1 | CYSLTR2 1413/4885CYSLTR1 1563/4885CYP1A2 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.