Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220847 | 0.82 | ALDH1A1 (0.48) | CA1CA2ALDH1A1KDM4EKMT2A | |
| SCHEMBL19669833 | 0.81 | ALDH1A1 (0.54) | CA1CA2ALDH1A1KDM4EKMT2A | |
| SCHEMBL10927250 | 0.81 | CYP3A4 (0.45) | CA1CA2ALDH1A1KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL10931915 | 0.79 | CA1 (0.44) | CA1CA2ALDH1A1KDM4EKMT2A | |
| SCHEMBL10926381 | 0.79 | CA1 (0.41) | CA1CA2ALDH1A1KDM4EKMT2A | |
| SCHEMBL10926384 | 0.79 | CA1 (0.41) | CA1CA2ALDH1A1KDM4EKMT2A | |
| SCHEMBL9427437 | 0.78 | CA1 (0.46) | CA1CA2ALDH1A1KDM4EKMT2A | |
| SCHEMBL10928173 | 0.78 | CA1 (0.42) | CA1CA2ALDH1A1KDM4EKMT2A | |
| SCHEMBL10928166 | 0.78 | CA1 (0.42) | CA1CA2ALDH1A1KDM4EKMT2A | |
| SCHEMBL27746629 | 0.78 | ALDH1A1 (0.44) | CA1CA2ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296482-A | (Benzocycloalkyl) alkylamines | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |
| EP-0534859-A1 | Benzocyclobutyl- or indanyl-alkyl-amino-alkyl substituted 3-benzazepin-2-ones useful in the treatment of cardiovascular diseases | ADIR ET COMPAGNIE (FR) | 1993-03-31 | — | — | EP | disclosed |