Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.62 |
| ▸ | HRH2 | P25021 | 11/20 | 0.38 |
| ▸ | HRH1 | P35367 | 11/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7445269 | 0.99 | ITGB3 (0.61) | ITGB3ITGA2BHRH2HRH1EPHX2 | |
| SCHEMBL7449422 | 0.98 | ITGB3 (0.61) | ITGB3ITGA2BHRH2HRH1EPHX2 | |
| Hydrochloric Acid SCHEMBL7454956 | 0.97 | ITGB3 (0.60) | ITGB3ITGA2BHRH2HRH1EPHX2 | |
| SCHEMBL7446744 | 0.95 | ITGB3 (0.64) | ITGB3ITGA2BHRH2HRH1MAPT | |
| Hydrochloric Acid SCHEMBL7449815 | 0.95 | ITGB3 (0.63) | ITGB3ITGA2BHRH2HRH1MAPT | |
| SCHEMBL7447020 | 0.92 | ITGB3 (0.73) | ITGB3ITGA2BHPGDHSD17B10FPR2 | |
| Hydrochloric Acid SCHEMBL7447015 | 0.92 | ITGB3 (0.72) | ITGB3ITGA2BHPGDHSD17B10FPR2 | |
| SCHEMBL7444447 | 0.91 | ITGB3 (0.62) | ITGB3ITGA2BEPHX2HPGDFPR2 | |
| SCHEMBL7450550 | 0.89 | ITGB3 (0.70) | ITGB3ITGA2BHRH2HRH1EPHX2 | |
| SCHEMBL7446668 | 0.89 | ITGB3 (0.61) | ITGB3ITGA2BHRH2HRH1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025358-A | Double prodrugs of potent GP IIb/IIIa antagonists | G. D. SEARLE & CO. (US) | 2000-02-15 | — | — | US | claimed |
| WO-1999064397-A1 | DOUBLE PRODRUGS OF POTENT GPIIb/IIIa ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-12-16 | — | — | WO | claimed |
| US-6025358-A | Double prodrugs of potent GP IIb/IIIa antagonists | G. D. SEARLE & CO. (US) | 2000-02-15 | — | — | US | disclosed |
| WO-1999064397-A1 | DOUBLE PRODRUGS OF POTENT GPIIb/IIIa ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-12-16 | — | — | WO | disclosed |