SCHEMBL74453

SCHEMBL74453

[CH2]n1cncn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2513229 0.64
SCHEMBL665120 0.63
SCHEMBL24211656 0.63 ALDH1A1 (0.35)
SCHEMBL155596 0.63
SCHEMBL9697494 0.62
SCHEMBL7841814 0.60 POLB (0.37)
SCHEMBL7841816 0.60 POLB (0.37)
SCHEMBL12578966 0.60
SCHEMBL6356094 0.57
SCHEMBL7810598 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 909 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3921320-B1 IMIDAZO [2, 1-F] [1, 2, 4] TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST BEIGENE LTD (KY) 2024-03-06 EP claimed
US-20220389009-A1 SUBSTITUTED 1,6-NAPHTHYRIDINE INHIBITORS OF CDK5 GFB (ABC), LLC 2022-12-08 US claimed
CN-114761000-A Substituted 1, 6-naphthyridine inhibitors of CDK5 金翅雀生物公司 2022-07-15 CN claimed
US-20220119394-A1 IMIDAZO[2,1-F][1,2,4]TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST BEONE MEDICINES I GMBH (CH) 2022-04-21 US claimed
WO-2022026823-A1 CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF CHAN ZUCKERBERG BIOHUB, INC. (US) 2022-02-03 WO claimed
WO-2022011274-A1 SUBSTITUTED 1,6-NAPHTHYRIDINE INHIBITORS OF CDK5 GOLDFINCH BIO, INC. (US) 2022-01-13 WO claimed
CN-113454086-A Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR7 agonists 百济神州有限公司 2021-09-28 CN claimed
CN-109743878-B Suspension and grinding method 昭和电工材料株式会社 2021-07-06 CN claimed
CN-107709658-B Oxidation process 卡特克塞尔科技有限公司 2021-04-09 CN claimed
WO-2021067569-A1 SUBSTITUTED 1, 6-NAPHTHYRIDINE INHIBITORS OF CDK5 GOLDFINCH BIO, INC. (US) 2021-04-08 WO claimed
US-4438125-A PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1984-03-20 US claimed
EP-0044482-B1 N-ALLENYLALKYL-ACETANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1983-11-16 EP claimed
US-4377587-A FUNGICIDE CIBA-GEIGY CORPORATION (US) 1983-03-22 US claimed
EP-0056589-A1 N-substituted anilides, process for their preparation and their use as fungicides BAYER AG (DE) 1982-07-28 EP claimed
EP-0056161-A2 Hydroximic acid esters, their preparation and their use as fungicides BAYER AG (DE) 1982-07-21 EP claimed
EP-0046931-A2 N-oxiamide, preparation thereof and use thereof as fungicide BAYER AG (DE) 1982-03-10 EP claimed
EP-0045049-A2 Arylamine derivatives, process for their preparation and their use as microbicides CIBA-GEIGY AG (CH) 1982-02-03 EP claimed
EP-0044482-A2 N-allenylalkyl-acetanilides, process for their preparation and their use as fungicides BAYER AG (DE) 1982-01-27 EP claimed
EP-0030923-A1 3-(N-acyl-phenylamino)-2-oxazolidinones, process for their preparation and their use as microbicides or in microbicidal agents CIBA-GEIGY AG (CH) 1981-06-24 EP claimed
EP-0028011-A1 Homoserin derivatives, process for their preparation and their use as microbicides CIBA-GEIGY AG (CH) 1981-05-06 EP claimed