Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.76 |
| ▸ | ACE | P12821 | 2/20 | 0.67 |
| ▸ | CPA1 | P15085 | 1/20 | 0.67 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.67 |
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.60 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6173139 | 0.87 | MME (0.86) | MMEHRH4 | |
| SCHEMBL6173142 | 0.87 | MME (0.86) | MMEHRH4 | |
| SCHEMBL6170941 | 0.86 | MME (1.00) | MMEACEHRH4 | |
| SCHEMBL6170943 | 0.86 | MME (1.00) | MMEACEHRH4 | |
| SCHEMBL6170689 | 0.85 | ECE1 (0.66) | MMEACE | |
| SCHEMBL6168678 | 0.85 | MME (0.82) | MMEACECPA1ACE2HRH4 | |
| SCHEMBL6171524 | 0.85 | MME (0.82) | MMEACECPA1ACE2HRH4 | |
| SCHEMBL6169325 | 0.84 | ACE (0.74) | MMEACECPA1ACE2 | |
| SCHEMBL6169327 | 0.84 | ACE (0.74) | MMEACECPA1ACE2 | |
| SCHEMBL6171856 | 0.83 | PPARG (0.62) | MMEACECPA1ACE2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262436-A | Administering; enzyme inhibitor | SCHERING CORPORATION (US) | 1993-11-16 | — | — | US | disclosed |
| US-4929641-A | DIURETICS, ANGIOTENSIN CONVERTING ENZYMES | SCHERING CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |
| US-4801609-A | Mercapto-acylamino acid antihypertensives | SCHERING CORPORATION (US) | 1989-01-31 | — | — | US | disclosed |