SCHEMBL7445576

SCHEMBL7445576

CC(O)C=CCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1931727 0.76
SCHEMBL29886820 0.76
SCHEMBL1931724 0.76
SCHEMBL1792220 0.72
SCHEMBL10657183 0.72
Isopropyl Alcohol SCHEMBL27481608 0.72
SCHEMBL501309 0.69
SCHEMBL5868371 0.69 ALDH1A1 (0.39)
SCHEMBL5868370 0.69 ALDH1A1 (0.39)
SCHEMBL231877 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1098252-C Method for producing 2-hydroxy-4- (methylthio) butanoic acid or methionine by thiol addition NOVOUS INTERNAT INC (US) 2003-01-08 CN claimed
CN-1244192-A Process for the preparation of 2-hydroxy-4-(methylthio) butanoic acid or methionine by mercaptan addition NOVOUS INTERNATIONAL INC (US) 2000-02-09 CN claimed
JP-6087892-A None JP disclosed
EP-3668883-A1 ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES Agilent Technologies, Inc. (US) 2020-06-24 EP disclosed
WO-2019036029-A1 ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES AGILENT TECHNOLOGIES, INC. (US) 2019-02-21 WO disclosed
CN-1098252-C Method for producing 2-hydroxy-4- (methylthio) butanoic acid or methionine by thiol addition NOVOUS INTERNAT INC (US) 2003-01-08 CN disclosed
CN-1244192-A Process for the preparation of 2-hydroxy-4-(methylthio) butanoic acid or methionine by mercaptan addition NOVOUS INTERNATIONAL INC (US) 2000-02-09 CN disclosed
EP-0800515-A1 DIBENZ cd,f]INDOLE DERIVATIVES Novartis AG (CH) 1997-10-15 EP disclosed
WO-1996020927-A1 DIBENZ[cd,f]INDOLE DERIVATIVES NOVARTIS AG (CH) 1996-07-11 WO disclosed
EP-0504812-B1 Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1995-09-06 EP disclosed
US-5302619-A Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-04-12 US disclosed
JP-H0687892-A AXINASTATIN 1 UNIV ARIZONA FOUND 1994-03-29 JP disclosed
US-5262441-A APPLYING INSECTICIDE TO INSECT OR LOCUS WHERE INSECT PROPAGATES SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1993-11-16 US disclosed
EP-0528583-A1 Isolation and structure of the cell growth inhibitory cycloheptapeptide axinastatin 1 ARIZONA BOARD OF REGENTS (US) 1993-02-24 EP disclosed
EP-0504812-A2 Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-09-23 EP disclosed
US-5061720-A ANTIINFLAMMATORY AGENTS FOR TOPICAL APPLICATION TO SKIN A. H. ROBINS COMPANY, INC. (US) 1991-10-29 US disclosed
US-5011992-A Antiemetics BRISTOL-MYERS SQUIBB COMPANY (US) 1991-04-30 US disclosed
US-4820715-A TREATING NAUSEA AND GASTRIC DISORDERS BRISTOL-MYERS COMPANY (US) 1989-04-11 US disclosed
US-4808624-A ANTIEMETICS BRISTOL-MYERS COMPANY (US) 1989-02-28 US disclosed
US-4602032-A Dibenz[cd,f]indole derivatives, their preparation and pharmaceutical compositions containing them SANDOZ LTD. (CH) 1986-07-22 US disclosed