Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 16/20 | 0.45 |
| ▸ | EDNRB | P24530 | 5/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DHPS | P49366 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441080 | 0.89 | EDNRA (0.45) | EDNRAEDNRBALDH1A1TSHRDHPS | |
| SCHEMBL7850046 | 0.84 | EDNRA (0.59) | EDNRAEDNRBDHPS | |
| SCHEMBL6972565 | 0.83 | EDNRA (0.47) | EDNRAEDNRBALDH1A1LMNATSHR | |
| SCHEMBL7889730 | 0.83 | EDNRA (0.62) | EDNRAEDNRB | |
| SCHEMBL7892848 | 0.81 | EDNRA (0.63) | EDNRAEDNRB | |
| SCHEMBL7305825 | 0.78 | EDNRA (0.61) | EDNRAEDNRBDHPS | |
| SCHEMBL1259727 | 0.75 | EDNRA (0.69) | EDNRAEDNRB | |
| SCHEMBL5499789 | 0.75 | EDNRA (0.63) | EDNRAEDNRBDHPS | |
| SCHEMBL7446457 | 0.74 | EDNRA (0.65) | EDNRAEDNRBDHPS | |
| SCHEMBL6957003 | 0.74 | EDNRA (0.47) | EDNRAEDNRBDHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799209-A1 | NOVEL SULFONAMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996019459-A1 | NOVEL SULFONAMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 1996-06-27 | — | — | WO | disclosed |