Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | F2R | P25116 | 3/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | YAP1 | P46937 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444755 | 0.93 | ITGB3 (0.56) | ITGB3ITGA2BF2RGPR119KMT2A | |
| SCHEMBL7504289 | 0.91 | ITGB3 (0.52) | ITGB3ITGA2BALDH1A1F2RGPR119 | |
| SCHEMBL7501689 | 0.91 | ITGB3 (0.52) | ITGB3ITGA2BALDH1A1F2RGPR119 | |
| SCHEMBL7446950 | 0.87 | KDM4E (0.53) | ITGB3ITGA2BALDH1A1F2RGPR119 | |
| SCHEMBL6936056 | 0.87 | ITGB3 (0.69) | ITGB3ITGA2BALDH1A1F2RGPR119 | |
| SCHEMBL7450055 | 0.86 | ITGB3 (0.42) | ITGB3ITGA2BALDH1A1GPR119KMT2A | |
| SCHEMBL7506218 | 0.85 | ITGB3 (0.49) | ITGB3ITGA2BALDH1A1F2RKMT2A | |
| SCHEMBL7503244 | 0.85 | ITGB3 (0.50) | ITGB3ITGA2BALDH1A1F2RGPR119 | |
| SCHEMBL7445811 | 0.85 | ITGB3 (0.52) | ITGB3ITGA2BALDH1A1F2RL3MBTL1 | |
| SCHEMBL7445639 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2BALDH1A1F2RKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384028-B1 | TREATMENT OF CARDIOVASCULAR DISORDERS, ANTICOAGULANTS AND VALVE REPLACEMENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-0869944-A1 | N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |
| WO-1996029309-A1 | N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-26 | — | — | WO | disclosed |