Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | MC3R | P41968 | 1/20 | 0.44 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3421625 | 0.93 | AKR1C3 (0.49) | ALOX5CYP1A2NR1H4MEN1KMT2A | |
| SCHEMBL3425725 | 0.91 | PTGS1 (0.43) | ALOX5CYP1A2NR1H4MEN1KMT2A | |
| SCHEMBL6371684 | 0.83 | NR1H4 (0.49) | ALOX5CYP1A2NR1H4MEN1KMT2A | |
| SCHEMBL226474 | 0.83 | CYP1A2 (0.61) | CYP1A2SLC6A3SLC13A5PDPK1 | |
| SCHEMBL3700625 | 0.81 | CYP1A2 (0.54) | ALOX5CYP1A2NR1H4MEN1KMT2A | |
| SCHEMBL30345756 | 0.81 | CYP1A2 (0.54) | ALOX5CYP1A2NR1H4MEN1KMT2A | |
| 2-Naphthylacetic Acid SCHEMBL29180271 | 0.81 | NR1H4 (0.67) | ALOX5CYP1A2NR1H4MEN1KMT2A | |
| 2-Naphthylacetic Acid SCHEMBL11102091 | 0.81 | NR1H4 (0.67) | ALOX5CYP1A2NR1H4MEN1KMT2A | |
| SCHEMBL24241927 | 0.81 | CYP1A2 (0.52) | ALOX5CYP1A2NR1H4MEN1KMT2A | |
| 2-Naphthylacetic Acid SCHEMBL30493868 | 0.81 | NR1H4 (0.71) | ALOX5CYP1A2NR1H4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109956867-A | For the acrylic ester compound of coating, preparation method and include its coating and purposes | 无锡阿科力科技股份有限公司 | 2019-07-02 | — | — | CN | disclosed |
| US-5262436-A | Administering; enzyme inhibitor | SCHERING CORPORATION (US) | 1993-11-16 | — | — | US | disclosed |
| EP-0566157-A1 | Neutral metalloendopeptidase inhibitors in the treatment of hypertension | SCHERING CORPORATION (US) | 1993-10-20 | — | — | EP | disclosed |
| US-5061710-A | Atrial natriuretic factors | SCHERING CORPORATION (US) | 1991-10-29 | — | — | US | disclosed |
| US-5030568-A | Bioconversion of naphthalene monomers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-07-09 | — | — | US | disclosed |
| US-4929641-A | DIURETICS, ANGIOTENSIN CONVERTING ENZYMES | SCHERING CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |
| US-4801609-A | Mercapto-acylamino acid antihypertensives | SCHERING CORPORATION (US) | 1989-01-31 | — | — | US | disclosed |