Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.63 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.59 |
| ▸ | TUBB | P07437 | 4/20 | 0.59 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.59 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.59 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.59 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.59 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.59 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.59 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.59 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.59 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.59 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.59 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.59 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.59 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440035 | 0.89 | TUBB4A (0.62) | ATMTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL11356640 | 0.84 | ATM (0.66) | ATMTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28950301 | 0.80 | TUBB4A (0.57) | ATMTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6378725 | 0.80 | TUBB4A (0.66) | ATMTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7437553 | 0.80 | GSK3B (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13662944 | 0.79 | ATM (0.59) | ATMTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL59900 | 0.79 | MAPT (0.62) | CYP3A4MAPT | |
| Schisandrin A SCHEMBL29354946 | 0.78 | ATM (1.00) | ATMTUBB4ATUBBTUBA3CTUBA1B | |
| Schisandrin A SCHEMBL2404905 | 0.78 | ATM (1.00) | ATMTUBB4ATUBBTUBA3CTUBA1B | |
| Schisandrin A SCHEMBL2703836 | 0.78 | ATM (1.00) | ATMTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321135-A | Process for the preparation of polycyclic compounds using ferric perchlorate and acid trifluoroacidic | TSUMURA & CO. (JP) | 1994-06-14 | — | — | US | disclosed |
| EP-0594890-A1 | Polycyclic compounds, their preparation and their use as phosphodiesterases inhibitors | TSUMURA & CO. (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0511666-A1 | Process for the preparation of polycyclic compounds | TSUMURA & CO. (JP) | 1992-11-04 | — | — | EP | disclosed |