Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438567 | 0.87 | ELANE (0.63) | ELANECTRB1CTSLP2RX7ALDH1A1 | |
| SCHEMBL6506922 | 0.84 | ELANE (0.41) | ELANECTRB1ALDH1A1LMNAHPGD | |
| SCHEMBL7851384 | 0.84 | ELANE (0.49) | ELANECTRB1ACECTSLALDH1A1 | |
| SCHEMBL6801336 | 0.81 | ELANE (0.38) | ELANELMNANPC1 | |
| SCHEMBL7444707 | 0.81 | ELANE (0.39) | ELANECTRB1ACECTSLKMT2A | |
| SCHEMBL6801293 | 0.81 | ELANE (0.41) | ELANEALDH1A1LMNAHPGDHTT | |
| SCHEMBL6497577 | 0.79 | ELANE (0.40) | ELANELMNAKMT2A | |
| SCHEMBL6805137 | 0.78 | ELANE (0.39) | ELANELMNAKMT2ANPC1 | |
| SCHEMBL6801500 | 0.78 | ELANE (0.42) | ELANECTRB1HPGDKMT2ANPC1 | |
| SCHEMBL7445664 | 0.78 | ELANE (0.40) | ELANELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996037485-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1996-11-28 | — | — | WO | disclosed |