Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8490497 | 0.93 | ITGB3 (0.40) | CRHBPCRHR2ITGB3ITGA2BHTT | |
| SCHEMBL7443343 | 0.92 | ITGB3 (0.37) | CRHBPCRHR2ITGB3ITGA2BKMT2A | |
| Acetic Acid SCHEMBL8476499 | 0.92 | ITGB3 (0.39) | CRHBPCRHR2ITGB3ITGA2BHTT | |
| Hydrochloric Acid SCHEMBL7446793 | 0.92 | ITGB3 (0.39) | CRHBPCRHR2ITGB3ITGA2BHTT | |
| Hydrochloric Acid SCHEMBL7438834 | 0.92 | ITGB3 (0.39) | CRHBPCRHR2ITGB3ITGA2BHTT | |
| Hydrochloric Acid SCHEMBL8488366 | 0.92 | ITGB3 (0.39) | CRHBPCRHR2ITGB3ITGA2BHTT | |
| Hydrochloric Acid SCHEMBL8481921 | 0.92 | ITGB3 (0.39) | CRHBPCRHR2ITGB3ITGA2BHTT | |
| SCHEMBL7451003 | 0.91 | ITGB3 (0.36) | CRHBPCRHR2ITGB3ITGA2BHTT | |
| SCHEMBL7451749 | 0.89 | MEN1 (0.39) | CRHBPCRHR2ITGB3ITGA2BHTT | |
| SCHEMBL7505335 | 0.88 | CYP3A4 (0.35) | CRHBPCRHR2ITGB3ITGA2BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729460-B1 | SUBSTITUTED 5-RING HETEROCYCLES, THEIR PREPARATION AND THEIR USE | HOECHST AG (DE) | 2002-05-15 | — | — | EP | disclosed |
| WO-1995014008-A1 | SUBSTITUTED 5-RING HETEROCYCLES, THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-26 | — | — | WO | disclosed |