Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11879376 | 0.75 | KDM4E (0.54) | KDM4ECYP3A4TDP1FDPSHCAR1 | |
| SCHEMBL11870805 | 0.71 | KDM4E (0.46) | KDM4ECYP3A4TDP1HCAR1ALDH1A1 | |
| SCHEMBL828619 | 0.69 | KMT2A (0.57) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11882632 | 0.69 | KMT2A (0.57) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8013328 | 0.69 | FGFR1 (0.54) | KDM4EHCAR1ALDH1A1HPGDHTT | |
| Bromide SCHEMBL7400039 | 0.68 | KMT2A (0.55) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7611308 | 0.68 | KMT2A (0.55) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL738023 | 0.68 | KMT2A (0.55) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL28464453 | 0.68 | KDM4E (0.42) | KDM4ECYP3A4TDP1HCAR1ALDH1A1 | |
| Carbamic Acid SCHEMBL10888970 | 0.67 | SMN1; SMN2 (0.56) | KDM4EMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001042224-A1 | CARBOXYAMIDO DERIVATIVES | MITSUBISHI PHARMA CORPORATION (JP) | 2001-06-14 | — | — | WO | disclosed |