Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.52 |
| ▸ | KLK1 | P06870 | 3/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7453241 | 0.93 | F2 (0.48) | F2KLK1KLK5 | |
| SCHEMBL7445943 | 0.93 | F2 (0.53) | F2KLK1KLK5 | |
| Hydrochloric Acid SCHEMBL7447409 | 0.92 | F2 (0.46) | F2KLK1KLK5 | |
| SCHEMBL7445168 | 0.90 | F2 (0.51) | F2KLK1KLK5 | |
| Hydrochloric Acid SCHEMBL7449253 | 0.89 | F2 (0.50) | F2KLK1KLK5 | |
| SCHEMBL7448557 | 0.89 | F2 (0.42) | F2KLK1KLK5 | |
| SCHEMBL7446295 | 0.89 | KLK1 (0.44) | F2KLK1KLK5 | |
| Hydrochloric Acid SCHEMBL7442296 | 0.88 | F2 (0.44) | F2KLK1KLK5 | |
| SCHEMBL7449323 | 0.88 | F2 (0.49) | F2KLK1KLK5 | |
| Hydrochloric Acid SCHEMBL7449067 | 0.88 | KLK1 (0.45) | F2KLK1KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966454-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES, THEIR PRODUCTION AND USE AS MEDICAMENTS | Boehringer Ingelheim Pharma KG (DE) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998037075-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES, THEIR PRODUCTION AND USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1998-08-27 | — | — | WO | disclosed |