Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.55 |
| ▸ | F2 | P00734 | 3/20 | 0.54 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 4/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | EBP | Q15125 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7502080 | 0.88 | F2 (0.66) | LTA4HF2ESR1ESR2 | |
| SCHEMBL7440123 | 0.85 | LTA4H (0.62) | LTA4HF2PSMB1PSMB5PSMB2 | |
| SCHEMBL7441003 | 0.83 | LTA4H (0.55) | LTA4HF2PSMB1PSMB5PSMB2 | |
| SCHEMBL228920 | 0.82 | LTA4H (0.72) | LTA4HPSMB1PSMB5PSMB2ESR1 | |
| SCHEMBL7452240 | 0.81 | F2 (0.56) | LTA4HF2PSMB1PSMB5PSMB2 | |
| SCHEMBL227053 | 0.80 | LTA4H (0.60) | LTA4HPSMB1PSMB5PSMB2ESR1 | |
| SCHEMBL6594039 | 0.79 | F2 (0.81) | F2ESR1ESR2 | |
| SCHEMBL7442661 | 0.79 | F2 (0.58) | LTA4HF2PSMB1PSMB5PSMB2 | |
| SCHEMBL7503435 | 0.78 | LTA4H (0.53) | LTA4HPSMB1PSMB5PSMB2ESR1 | |
| SCHEMBL7349591 | 0.78 | LTA4H (0.70) | LTA4HPSMB1PSMB5PSMB2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |