Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 18/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 18/20 | 0.48 |
| ▸ | F2R | P25116 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440100 | 0.92 | ITGB3 (0.57) | KDM4EPKMITGB3ITGA2BF2R | |
| SCHEMBL7498839 | 0.90 | KDM4E (0.51) | KDM4EPKMITGB3ITGA2BF2R | |
| SCHEMBL7501692 | 0.88 | ITGB3 (0.63) | ITGB3ITGA2BF2R | |
| SCHEMBL7451616 | 0.88 | ITGB3 (0.47) | ITGB3ITGA2BF2R | |
| SCHEMBL7504283 | 0.88 | ITGB3 (0.54) | ITGB3ITGA2BF2R | |
| SCHEMBL7446950 | 0.87 | KDM4E (0.53) | KDM4EPKMITGB3ITGA2BF2R | |
| SCHEMBL7445811 | 0.86 | ITGB3 (0.52) | ITGB3ITGA2BF2R | |
| SCHEMBL7506215 | 0.85 | ITGB3 (0.50) | ITGB3ITGA2BF2R | |
| SCHEMBL7498836 | 0.85 | ITGB3 (0.54) | KDM4EPKMITGB3ITGA2BF2R | |
| SCHEMBL7503248 | 0.85 | ITGB3 (0.62) | ITGB3ITGA2BF2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384028-B1 | TREATMENT OF CARDIOVASCULAR DISORDERS, ANTICOAGULANTS AND VALVE REPLACEMENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-0869944-A1 | N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |
| WO-1996029309-A1 | N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-26 | — | — | WO | disclosed |