Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.45 |
| ▸ | F2R | P25116 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | YAP1 | P46937 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442054 | 0.91 | ITGB3 (0.46) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7462645 | 0.84 | ITGB3 (0.41) | ITGB3ITGA2BMEN1ALDH1A1MAPT | |
| SCHEMBL7446981 | 0.84 | ITGB3 (0.39) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7443488 | 0.84 | ITGB3 (0.44) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7446988 | 0.84 | MEN1 (0.41) | ITGB3ITGA2BMEN1ALDH1A1MAPT | |
| SCHEMBL7446210 | 0.83 | ITGB3 (0.60) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7444301 | 0.83 | GAA (0.41) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7467602 | 0.83 | GAA (0.41) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7451456 | 0.83 | HPGD (0.38) | ITGB3ITGA2BMEN1ALDH1A1MAPT | |
| SCHEMBL7442051 | 0.82 | KMT2A (0.42) | ITGB3ITGA2BMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384028-B1 | TREATMENT OF CARDIOVASCULAR DISORDERS, ANTICOAGULANTS AND VALVE REPLACEMENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| WO-1996029309-A1 | N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-26 | — | — | WO | disclosed |