Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.73 |
| ▸ | LTA4H | P09960 | 4/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.61 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.61 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.61 |
| ▸ | HRH1 | P35367 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8337754 | 0.95 | HRH3 (0.70) | HRH3LTA4HKDM4EPSMB1PSMB5 | |
| Hydrochloric Acid SCHEMBL8972891 | 0.93 | HRH3 (0.68) | HRH3LTA4HKDM4EPSMB1PSMB5 | |
| SCHEMBL82435 | 0.93 | HRH3 (0.73) | HRH3LTA4HKDM4EPSMB1PSMB5 | |
| SCHEMBL12035585 | 0.93 | HRH3 (0.73) | HRH3LTA4HKDM4EPSMB1PSMB5 | |
| Hydrochloric Acid SCHEMBL6473996 | 0.92 | HRH3 (0.71) | HRH3LTA4HKDM4EPSMB1PSMB5 | |
| SCHEMBL15834053 | 0.91 | HRH3 (0.66) | HRH3LTA4HKDM4EPSMB1PSMB5 | |
| SCHEMBL4089489 | 0.90 | HRH3 (0.84) | HRH3HRH1KCNH2 | |
| SCHEMBL7443460 | 0.87 | LTA4H (0.77) | HRH3LTA4HKDM4EPSMB1PSMB5 | |
| SCHEMBL2629440 | 0.86 | HRH3 (0.72) | HRH3KDM4EHRH1KCNH2ACHE | |
| SCHEMBL7135133 | 0.86 | LTA4H (0.73) | HRH3LTA4HPSMB1PSMB5PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |