Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.65 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.33 |
| ▸ | FPR1 | P21462 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444768 | 0.98 | ITGB3 (0.64) | ITGB3ITGA2BEPHX2CYP1A2FPR2 | |
| SCHEMBL7442322 | 0.95 | ITGB3 (0.67) | ITGB3ITGA2BEPHX2CYP1A2FPR2 | |
| SCHEMBL7445983 | 0.92 | ITGB3 (0.77) | ITGB3ITGA2BFPR2HDAC6FPR1 | |
| SCHEMBL7446731 | 0.92 | ITGB3 (0.60) | ITGB3ITGA2BEPHX2CYP1A2FPR2 | |
| SCHEMBL7450550 | 0.91 | ITGB3 (0.70) | ITGB3ITGA2BEPHX2FPR2MAPT | |
| Hydrochloric Acid SCHEMBL7450410 | 0.91 | ITGB3 (0.60) | ITGB3ITGA2BEPHX2CYP1A2FPR2 | |
| SCHEMBL7451987 | 0.90 | ITGB3 (0.60) | ITGB3ITGA2BEPHX2CYP1A2FPR2 | |
| SCHEMBL7449435 | 0.89 | ITGB3 (0.61) | ITGB3ITGA2BEPHX2CYP1A2FPR2 | |
| SCHEMBL7446800 | 0.89 | ITGB3 (0.64) | ITGB3ITGA2BEPHX2FPR2HDAC6 | |
| Water SCHEMBL7450330 | 0.89 | ITGB3 (0.59) | ITGB3ITGA2BEPHX2CYP1A2FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025358-A | Double prodrugs of potent GP IIb/IIIa antagonists | G. D. SEARLE & CO. (US) | 2000-02-15 | — | — | US | claimed |
| WO-1999064397-A1 | DOUBLE PRODRUGS OF POTENT GPIIb/IIIa ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-12-16 | — | — | WO | claimed |
| US-6025358-A | Double prodrugs of potent GP IIb/IIIa antagonists | G. D. SEARLE & CO. (US) | 2000-02-15 | — | — | US | disclosed |
| WO-1999064397-A1 | DOUBLE PRODRUGS OF POTENT GPIIb/IIIa ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-12-16 | — | — | WO | disclosed |