Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 4/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.36 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17828018 | 0.81 | P2RX7 (0.56) | P2RX7GRM5CTNNB1WNT3ACTSA | |
| SCHEMBL5311440 | 0.79 | P2RX7 (0.54) | P2RX7GRM5CTNNB1WNT3ACTSA | |
| SCHEMBL30693375 | 0.77 | P2RX7 (0.59) | P2RX7GRM5CTSARAB9ACYP1A2 | |
| SCHEMBL5067835 | 0.77 | P2RX7 (0.59) | P2RX7GRM5CTSARAB9ACYP1A2 | |
| SCHEMBL17820410 | 0.77 | P2RX7 (0.65) | P2RX7GRM5CTSARAB9ACYP1A2 | |
| SCHEMBL15979671 | 0.77 | GRM5 (0.57) | P2RX7GRM5CTNNB1WNT3ACTSA | |
| SCHEMBL17820595 | 0.75 | P2RX7 (0.54) | P2RX7GRM5CTSARAB9ACYP1A2 | |
| SCHEMBL4307414 | 0.75 | P2RX7 (0.58) | P2RX7GRM5CTSARAB9ACYP1A2 | |
| SCHEMBL30744821 | 0.75 | P2RX7 (0.58) | P2RX7GRM5CTSARAB9ACYP1A2 | |
| Hydrochloric Acid SCHEMBL6110884 | 0.74 | P2RX7 (0.61) | P2RX7GRM5CTSARAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000003712-A1 | 1-4-DIHYDROPYRIDINES WITH PYRIDINYL GROUP AS CALCIUM BLOCKERS | LABORATOIRE L. LAFON (FR) | 2000-01-27 | — | — | WO | disclosed |