Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.72 |
| ▸ | MME | P08473 | 10/20 | 0.72 |
| ▸ | XIAP | P98170 | 1/20 | 0.52 |
| ▸ | F7 | P08709 | 2/20 | 0.47 |
| ▸ | F3 | P13726 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447485 | 1.00 | ACE (0.72) | ACEMMEXIAPF7F3 | |
| SCHEMBL7442313 | 0.86 | ACE (0.76) | ACEMMEXIAP | |
| SCHEMBL7442308 | 0.86 | ACE (0.76) | ACEMMEXIAP | |
| SCHEMBL7440414 | 0.84 | ACE (1.00) | ACEMME | |
| SCHEMBL7341608 | 0.84 | ACE (1.00) | ACEMME | |
| SCHEMBL7440402 | 0.84 | ACE (1.00) | ACEMME | |
| SCHEMBL7341603 | 0.84 | ACE (1.00) | ACEMME | |
| SCHEMBL7440309 | 0.83 | ACE (0.72) | ACEMMEXIAP | |
| SCHEMBL8837682 | 0.83 | MME (0.73) | ACEMMEXIAP | |
| SCHEMBL7437629 | 0.83 | ACE (0.72) | ACEMMEXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994026719-A1 | MERCAPTO-AMIDE DERIVATIVES USEFUL AS NEUTRAL ENDOPEPTIDASE AND ACE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-24 | — | — | WO | disclosed |