Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 12/20 | 0.73 |
| ▸ | ACE | P12821 | 12/20 | 0.73 |
| ▸ | XIAP | P98170 | 5/20 | 0.51 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8837688 | 1.00 | MME (0.73) | MMEACEXIAPRIPK1NPY1R | |
| SCHEMBL8428443 | 0.85 | MME (1.00) | MMEACE | |
| SCHEMBL7433496 | 0.83 | ACE (0.72) | MMEACEXIAP | |
| SCHEMBL7433488 | 0.83 | ACE (0.72) | MMEACEXIAP | |
| SCHEMBL7437629 | 0.83 | ACE (0.72) | MMEACEXIAP | |
| SCHEMBL7449038 | 0.83 | ACE (0.72) | MMEACEXIAP | |
| SCHEMBL7437620 | 0.83 | ACE (0.72) | MMEACEXIAP | |
| SCHEMBL7440309 | 0.83 | ACE (0.72) | MMEACEXIAP | |
| SCHEMBL7447490 | 0.83 | ACE (0.72) | MMEACEXIAP | |
| SCHEMBL7447485 | 0.83 | ACE (0.72) | MMEACEXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646276-A | ANGIOTENSIN CONVERTING ENZYME AND NEUTRAL ENDOPEPTIDASE INHIBITORS; CARDIOVASCULAR DISORDERS | BRISTOL-MYERS SQUIBB CO. (US) | 1997-07-08 | — | — | US | disclosed |