Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656046 | 0.74 | — | — | |
| SCHEMBL3861670 | 0.71 | — | — | |
| Urea SCHEMBL28179593 | 0.71 | HTT (0.36) | PARP1 | |
| SCHEMBL7326829 | 0.67 | — | — | |
| SCHEMBL7842653 | 0.65 | RAB9A (0.37) | — | |
| SCHEMBL3512368 | 0.65 | — | — | |
| SCHEMBL8079157 | 0.65 | PARP1 (0.33) | PARP1 | |
| SCHEMBL7676177 | 0.65 | HTT (0.44) | PARP1 | |
| SCHEMBL1040746 | 0.64 | NOTUM (0.32) | — | |
| SCHEMBL2852145 | 0.64 | NOTUM (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397365-A1 | Arylthiazolylimidazoles as 5HT3 Antagonists | PFIZER INC. (US) | 1990-11-14 | — | — | EP | disclosed |
| US-4914207-A | ANTIEMETICS | PFIZER INC. (US) | 1990-04-03 | — | — | US | disclosed |