Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | TACR2 | P21452 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.40 |
| ▸ | CDC25B | P30305 | 6/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.39 |
| ▸ | GJB2 | P29033 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440204 | 0.96 | NT5E (0.47) | NT5EBCHEACHEPDPK1MTOR | |
| SCHEMBL9386370 | 0.86 | BCHE (0.45) | NT5EBCHEACHEPDPK1MTOR | |
| SCHEMBL8596282 | 0.86 | BCHE (0.45) | NT5EBCHEACHEPDPK1MTOR | |
| SCHEMBL10408818 | 0.86 | BCHE (0.41) | NT5EBCHEACHEPDPK1MTOR | |
| SCHEMBL10408817 | 0.86 | BCHE (0.41) | NT5EBCHEACHEPDPK1MTOR | |
| SCHEMBL10408132 | 0.84 | NT5E (0.43) | NT5EBCHEACHEPDPK1MTOR | |
| SCHEMBL4244893 | 0.84 | BCHE (0.40) | NT5EBCHEACHEPDPK1MTOR | |
| SCHEMBL4244898 | 0.84 | BCHE (0.40) | NT5EBCHEACHEPDPK1MTOR | |
| SCHEMBL11673910 | 0.84 | NT5E (0.43) | NT5EBCHEACHEPDPK1MTOR | |
| SCHEMBL11673905 | 0.84 | NT5E (0.43) | NT5EBCHEACHEPDPK1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166212-A | Hypotensive agents, analgesics | CIBA-GEIGY CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| US-5096925-A | N-substituted butyramide derivatives | CIBA-GEIGY CORPORATION (US) | 1992-03-17 | — | — | US | disclosed |
| US-5021430-A | Enkephalinase inhibitors, analgesics, hypotensives | CIBA-GEIGY CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
| US-4939261-A | ANALGESICS, ANTIDEPRESSANTS, HYPOTENSIVE AGENTS, NEUROLEPTIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1990-07-03 | — | — | US | disclosed |
| EP-0185079-B1 | N-SUBSTITUTED BUTYRAMIDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1988-10-19 | — | — | EP | disclosed |
| EP-0225292-A2 | Certain N-substituted butyramide derivatives | CIBA-GEIGY AG (CH) | 1987-06-10 | — | — | EP | disclosed |
| EP-0185079-A1 | — | CIBA GEIGY AG | 1986-06-25 | — | — | EP | disclosed |
| WO-1986000066-A1 | N-SUBSTITUTED BUTYRAMIDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1986-01-03 | — | — | WO | disclosed |