Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | TACR2 | P21452 | 3/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.38 |
| ▸ | CDC25B | P30305 | 6/20 | 0.38 |
| ▸ | GJB2 | P29033 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8596282 | 1.00 | BCHE (0.45) | BCHEACHEHTR1ANT5ETACR2 | |
| SCHEMBL7541321 | 0.96 | BCHE (0.44) | BCHEACHEHTR1ANT5ETACR2 | |
| SCHEMBL7908255 | 0.96 | BCHE (0.44) | BCHEACHEHTR1ANT5ETACR2 | |
| SCHEMBL7616207 | 0.96 | BCHE (0.44) | BCHEACHEHTR1ANT5ETACR2 | |
| SCHEMBL7544031 | 0.96 | BCHE (0.44) | BCHEACHEHTR1ANT5ETACR2 | |
| SCHEMBL7545172 | 0.96 | BCHE (0.44) | BCHEACHEHTR1ANT5ETACR2 | |
| SCHEMBL6428120 | 0.96 | BCHE (0.44) | BCHEACHEHTR1ANT5ETACR2 | |
| SCHEMBL6428124 | 0.96 | BCHE (0.44) | BCHEACHEHTR1ANT5ETACR2 | |
| SCHEMBL7447672 | 0.86 | NT5E (0.45) | BCHEACHEHTR1ANT5ETACR2 | |
| SCHEMBL11673910 | 0.84 | NT5E (0.43) | BCHEACHEHTR1ANT5ETACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6065281-A | — | — | None | — | — | JP | disclosed |
| CN-110615818-B | Synthesis method of fludarabine and nelarabine | 江西科技师范大学 | 2023-02-17 | — | — | CN | disclosed |
| CN-110615818-A | Synthesis method of fludarabine and nelarabine | 江西科技师范大学 | 2019-12-27 | — | — | CN | disclosed |
| JP-H0665281-A | IMPROVEMENT OF PREPARATION OF 2-AMINO(2,3,5-TRI-O-BENZYL-BETA-D-ARABINOFURANOSYL)ADENINE | ASH STEVENS INC | 1994-03-08 | — | — | JP | disclosed |