Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 7/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 7/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441356 | 0.95 | ITGB3 (0.57) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| SCHEMBL7447954 | 0.89 | ITGB3 (0.48) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| SCHEMBL7449755 | 0.87 | ITGB3 (0.52) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7447966 | 0.85 | KDM4E (0.37) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7448252 | 0.83 | ITGB3 (0.52) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| SCHEMBL7342234 | 0.83 | ITGB3 (0.59) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7341381 | 0.82 | ITGB3 (0.68) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| Iodomethane SCHEMBL9367655 | 0.81 | ITGB3 (0.57) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| SCHEMBL7441385 | 0.79 | KDM4E (0.40) | ITGB3ITGA2BALOX15MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7442158 | 0.78 | ITGB3 (0.56) | ITGB3ITGA2BALOX15MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623120-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014077-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |