Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 1/20 | 0.62 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.54 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.53 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.53 |
| ▸ | GGH | Q92820 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4947917 | 1.00 | GGT1 (0.62) | GGT1FOLH1NAALAD2RIMKLAGGH | |
| SCHEMBL28078777 | 1.00 | GGT1 (0.62) | GGT1FOLH1NAALAD2RIMKLAGGH | |
| SCHEMBL18814408 | 0.93 | GGT1 (0.56) | GGT1FOLH1NAALAD2RIMKLAGGH | |
| SCHEMBL29964294 | 0.89 | FOLH1 (0.53) | GGT1FOLH1NAALAD2RIMKLAGGH | |
| SCHEMBL8768068 | 0.87 | FOLH1 (0.61) | GGT1FOLH1NAALAD2RIMKLAGGH | |
| SCHEMBL8769194 | 0.87 | FOLH1 (0.61) | GGT1FOLH1NAALAD2RIMKLAGGH | |
| SCHEMBL29356795 | 0.87 | FOLH1 (0.61) | GGT1FOLH1NAALAD2RIMKLAGGH | |
| SCHEMBL141783 | 0.87 | FOLH1 (0.61) | GGT1FOLH1NAALAD2RIMKLAGGH | |
| SCHEMBL27546759 | 0.86 | GGT1 (0.61) | GGT1FOLH1NAALAD2RIMKLA | |
| SCHEMBL15387334 | 0.86 | GGT1 (0.61) | GGT1FOLH1NAALAD2RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973945-A4 | CHIRAL PEPTIDE NUCLEIC ACIDS AND METHODS FOR PREPARING SAME | ISIS PHARMACEUTICALS INC (US) | 2002-07-17 | — | — | EP | disclosed |
| EP-0973945-A1 | CHIRAL PEPTIDE NUCLEIC ACIDS AND METHODS FOR PREPARING SAME | ISIS PHARMACEUTICALS, INC. (US) | 2000-01-26 | — | — | EP | disclosed |
| US-6015887-A | PREPARING SYNTHETIC MONOMERS BY DEHYDRATIVE COUPLING OF AMINE AND ALCOHOL STARTING REAGENTS | ISIS PHARMACEUTICALS, INC. (US) | 2000-01-18 | — | — | US | disclosed |
| WO-1998046794-A1 | CHIRAL PEPTIDE NUCLEIC ACIDS AND METHODS FOR PREPARING SAME | ISIS PHARMACEUTICALS, INC. (US) | 1998-10-22 | — | — | WO | disclosed |