Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15660019 | 0.85 | GUSB (0.56) | L3MBTL1GAASMN1; SMN2CA2HSD17B1 | |
| SCHEMBL7445075 | 0.84 | GAA (0.64) | L3MBTL1GAASMN1; SMN2PKMCA1 | |
| SCHEMBL410747 | 0.84 | AR (0.67) | L3MBTL1GAASMN1; SMN2PKMCA1 | |
| SCHEMBL31235173 | 0.84 | AR (0.67) | L3MBTL1GAASMN1; SMN2PKMCA1 | |
| SCHEMBL17077916 | 0.83 | L3MBTL1 (0.65) | L3MBTL1GAASMN1; SMN2PKMCA1 | |
| SCHEMBL3625980 | 0.83 | L3MBTL1 (0.69) | L3MBTL1GAASMN1; SMN2PKMCA1 | |
| SCHEMBL28270283 | 0.83 | L3MBTL1 (0.65) | L3MBTL1GAASMN1; SMN2PKMCA1 | |
| SCHEMBL27176648 | 0.83 | L3MBTL1 (0.61) | L3MBTL1GAASMN1; SMN2PKMCA1 | |
| SCHEMBL27176681 | 0.81 | SMN1; SMN2 (0.64) | L3MBTL1GAASMN1; SMN2PKMCA1 | |
| SCHEMBL176826 | 0.81 | L3MBTL1 (0.66) | L3MBTL1GAASMN1; SMN2PKMCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777660-A1 | NOVEL ALKYLAMINO DERIVATIVES AS SIGMA 2 SELECTIVE LIGANDS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005185-A1 | NOVEL ALKYLAMINO DERIVATIVES AS SIGMA 2 SELECTIVE LIGANDS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-02-22 | — | — | WO | disclosed |