Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL4969304 | 0.87 | TDP1 (0.82) | TDP1TSHRSMN1; SMN2PTGDR2MRGPRX4 | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL5586016 | 0.86 | TDP1 (0.76) | TDP1TSHRHPGDSMN1; SMN2PTGDR2 | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL16197647 | 0.83 | TDP1 (1.00) | TDP1TSHRSMN1; SMN2PTGDR2MEN1 | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL158138 | 0.83 | TDP1 (1.00) | TDP1TSHRSMN1; SMN2PTGDR2MEN1 | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL9578938 | 0.83 | TDP1 (1.00) | TDP1TSHRSMN1; SMN2PTGDR2MEN1 | |
| SCHEMBL9772061 | 0.82 | HPGD (0.68) | TDP1TSHRHPGDSMN1; SMN2PTGDR2 | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL11224813 | 0.82 | TDP1 (0.97) | TDP1TSHRSMN1; SMN2PTGDR2MEN1 | |
| SCHEMBL14419386 | 0.81 | PTGDR2 (0.61) | TDP1TSHRHPGDSMN1; SMN2PTGDR2 | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL7445539 | 0.81 | TDP1 (0.80) | TDP1TSHRHPGDSMN1; SMN2PTGDR2 | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL5400218 | 0.80 | TDP1 (0.94) | TDP1TSHRSMN1; SMN2PTGDR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049708-A9 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | — | 1998-05-22 | — | — | WO | disclosed |