Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL66606 | 0.81 | MEN1 (0.48) | ALDH1A1HSD17B10TSHRTDP1ALOX15 | |
| SCHEMBL29959966 | 0.81 | MEN1 (0.48) | ALDH1A1HSD17B10TSHRTDP1ALOX15 | |
| SCHEMBL1332400 | 0.81 | MEN1 (0.48) | ALDH1A1HSD17B10TSHRTDP1ALOX15 | |
| SCHEMBL5526432 | 0.81 | MEN1 (0.48) | ALDH1A1HSD17B10TSHRTDP1ALOX15 | |
| SCHEMBL27537068 | 0.80 | ALDH1A1 (0.54) | ALDH1A1HSD17B10ALOX12L3MBTL1TSHR | |
| SCHEMBL31438814 | 0.78 | ALDH1A1 (0.52) | ALDH1A1HSD17B10ALOX12L3MBTL1TSHR | |
| SCHEMBL1300945 | 0.78 | TAAR1 (0.42) | ALDH1A1HPGDMAPTHTTMEN1 | |
| SCHEMBL9480018 | 0.77 | ALDH1A1 (0.62) | ALDH1A1HSD17B10ALOX12L3MBTL1TSHR | |
| SCHEMBL2035896 | 0.77 | ALDH1A1 (0.62) | ALDH1A1HSD17B10ALOX12L3MBTL1TSHR | |
| SCHEMBL27315184 | 0.77 | ALDH1A1 (0.62) | ALDH1A1HSD17B10ALOX12L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585500-A1 | Diaryl piperazineacetamides as antimuscarinic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-03-09 | — | — | EP | disclosed |