Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.56 |
| ▸ | FPR2 | P25090 | 5/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.36 |
| ▸ | FPR1 | P21462 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449484 | 0.95 | ITGB3 (0.55) | ITGB3ITGA2BFPR2HDAC6FPR1 | |
| Trifluoroacetic Acid SCHEMBL7442341 | 0.95 | ITGB3 (0.51) | ITGB3ITGA2BFPR2HDAC6FPR1 | |
| SCHEMBL7448991 | 0.93 | ITGB3 (0.60) | ITGB3ITGA2BFPR2HDAC6FPR1 | |
| Hydrochloric Acid SCHEMBL7450529 | 0.92 | ITGB3 (0.59) | ITGB3ITGA2BFPR2HDAC6FPR1 | |
| SCHEMBL7450166 | 0.91 | ITGB3 (0.60) | ITGB3ITGA2BFPR2HDAC6FPR1 | |
| SCHEMBL7454091 | 0.91 | ITGB3 (0.71) | ITGB3ITGA2BFPR2HDAC6FPR1 | |
| Water SCHEMBL7449648 | 0.90 | ITGB3 (0.59) | ITGB3ITGA2BFPR2HDAC6FPR1 | |
| SCHEMBL8101929 | 0.90 | ITGB3 (0.57) | ITGB3ITGA2BFPR2HDAC6FPR1 | |
| Hydrochloric Acid SCHEMBL7442895 | 0.90 | ITGB3 (0.70) | ITGB3ITGA2BFPR2HDAC6FPR1 | |
| SCHEMBL7449883 | 0.90 | ITGB3 (0.57) | ITGB3ITGA2BFPR2HDAC6FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025358-A | Double prodrugs of potent GP IIb/IIIa antagonists | G. D. SEARLE & CO. (US) | 2000-02-15 | — | — | US | claimed |
| WO-1999064397-A1 | DOUBLE PRODRUGS OF POTENT GPIIb/IIIa ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-12-16 | — | — | WO | claimed |
| WO-1999064397-A1 | DOUBLE PRODRUGS OF POTENT GPIIb/IIIa ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-12-16 | — | — | WO | disclosed |