SCHEMBL7448341

SCHEMBL7448341

CCCCC(CC)CNC(=O)NS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.66
CYP2C9 P11712 3/20 0.66
TSHR P16473 3/20 0.66
LMNA P02545 3/20 0.66
ALB P02768 1/20 0.66
TDP1 Q9NUW8 1/20 0.66
NPSR1 Q6W5P4 2/20 0.52
MAPT P10636 1/20 0.49
FBP1 P09467 1/20 0.48
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA9 Q16790 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
CYP3A4 P08684 1/20 0.47
THRB P10828 1/20 0.47
NFKB1 P19838 1/20 0.47
HTR2A P28223 1/20 0.47
CYP2C19 P33261 1/20 0.47
ADRA1A P35348 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3469704 0.81 GBA1 (0.55) ALDH1A1CYP2C9TSHRLMNAALB
Tolbutamide SCHEMBL1536920 0.80 ALDH1A1 (1.00) ALDH1A1CYP2C9TSHRLMNAALB
Tolbutamide SCHEMBL15918 0.80 ALDH1A1 (1.00) ALDH1A1CYP2C9TSHRLMNAALB
Tolbutamide SCHEMBL4367531 0.79 ALDH1A1 (0.97) ALDH1A1CYP2C9TSHRLMNAALB
Tolbutamide SCHEMBL140363 0.79 ALDH1A1 (0.97) ALDH1A1CYP2C9TSHRLMNAALB
Tolbutamide SCHEMBL11356450 0.79 ALDH1A1 (0.97) ALDH1A1CYP2C9TSHRLMNAALB
Tolbutamide SCHEMBL7551276 0.79 ALDH1A1 (0.97) ALDH1A1CYP2C9TSHRLMNAALB
Tolbutamide SCHEMBL11357518 0.79 ALDH1A1 (0.97) ALDH1A1CYP2C9TSHRLMNAALB
SCHEMBL8672470 0.79 ALDH1A1 (0.91) ALDH1A1CYP2C9TSHRLMNAALB
Tolbutamide SCHEMBL28046582 0.79 ALDH1A1 (0.97) ALDH1A1CYP2C9TSHRLMNAALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6416922-B2 DRY PROCESSING PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 2002-07-09 US disclosed
US-20010019806-A1 Azomethine dye precursor, image-forming material, and image-forming method FUJIFILM CORPORATION (JP) 2001-09-06 US disclosed